Table 2.
HIV status | Fracture location | Year of fracture | Sex | Age at fracture (years) | HTZ | WTZ | BMI z | Any NRTI | TDF | d4T | Any PI | CD4% | VL (copies/ml) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Infected | Femoral condyle | 2001 | M | 6.1 | −2.4 | 1.0 | 2.7 | Yes | No | Yes | Yes | 31 | 37,111 |
Infected | Leg | 2003 | F | 7.1 | 1.1 | 2.1 | 2.0 | Yes | No | No | Yes | 32 | 212 |
Infected | Tibia | 2006 | M | 5.9 | −1.2 | −0.8 | 0.1 | Yes | No | Yes | Yes | 21 | 42,100 |
Infected | Ankle | 2006 | M | 11.6 | 1.2 | 1.6 | 1.5 | Yes | No | Yes | No | 33 | 75 |
Infected | Femur | 2002 | F | 8.6 | 0.7 | 2.7 | 2.6 | No | No | No | No | 20 | 5,080 |
Infected | Ankle | 2006 | M | 12.3 | −0.7 | −0.4 | 0.1 | Yes | No | Yes | Yes | 28 | 8,630 |
Infected | Wrist | 2006 | F | 9.9 | −1.5 | −1.5 | −0.8 | Yes | No | Yes | No | 35 | 1,480 |
HEU | Humerus | 2006 | F | 6.2 | 2.6 | 2.3 | 1.6 | — | — | — | — | — | — |
HEU | Leg | 2005 | F | 9.9 | 0.3 | 0.0 | 0.0 | — | — | — | — | — | — |
HEU, HIV exposed but uninfected. Fracture location, year of fracture, sex, and age were at the time of fracture. Height z (HTZ), weight z (WTZ), and BMI z reflect values obtained at the time of fracture or at the last 219/219C visit before the fracture. Exception is for HEU subject with 2005 leg fracture for whom values from the first 219/219C visit after the fracture were used, since values at the prefracture visit were missing. Antiretroviral therapy, CD4%, and viral load were at the visit prior to the fracture. NRTI, nucleoside analogue reverse transcriptase inhibitor; TDF, tenofovir disoproxil fumarate; D4T, stavudine; PI, protease inhibitor; CD4%, last CD4+ T-lymphocyte percentage; VL, viral load (copies/ml); M, male; F, female.