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. 2012 Mar;28(3):247–250. doi: 10.1089/aid.2011.0064

Table 2.

Characteristics of the HIV-Infected and HIV-Exposed But Uninfected Children at or Near the Time of Fracture

HIV status Fracture location Year of fracture Sex Age at fracture (years) HTZ WTZ BMI z Any NRTI TDF d4T Any PI CD4% VL (copies/ml)
Infected Femoral condyle 2001 M 6.1 −2.4 1.0 2.7 Yes No Yes Yes 31 37,111
Infected Leg 2003 F 7.1 1.1 2.1 2.0 Yes No No Yes 32 212
Infected Tibia 2006 M 5.9 −1.2 −0.8 0.1 Yes No Yes Yes 21 42,100
Infected Ankle 2006 M 11.6 1.2 1.6 1.5 Yes No Yes No 33 75
Infected Femur 2002 F 8.6 0.7 2.7 2.6 No No No No 20 5,080
Infected Ankle 2006 M 12.3 −0.7 −0.4 0.1 Yes No Yes Yes 28 8,630
Infected Wrist 2006 F 9.9 −1.5 −1.5 −0.8 Yes No Yes No 35 1,480
HEU Humerus 2006 F 6.2 2.6 2.3 1.6
HEU Leg 2005 F 9.9 0.3 0.0 0.0

HEU, HIV exposed but uninfected. Fracture location, year of fracture, sex, and age were at the time of fracture. Height z (HTZ), weight z (WTZ), and BMI z reflect values obtained at the time of fracture or at the last 219/219C visit before the fracture. Exception is for HEU subject with 2005 leg fracture for whom values from the first 219/219C visit after the fracture were used, since values at the prefracture visit were missing. Antiretroviral therapy, CD4%, and viral load were at the visit prior to the fracture. NRTI, nucleoside analogue reverse transcriptase inhibitor; TDF, tenofovir disoproxil fumarate; D4T, stavudine; PI, protease inhibitor; CD4%, last CD4+ T-lymphocyte percentage; VL, viral load (copies/ml); M, male; F, female.