Figure 4.

Ordering of sequence groups and phylogeny violation in different regions of the enterovirus (EV) species c genome. A) Ordering of sequences from the three poliovirus serotypes (PV1 - PV3) and other enterovirus species serotypes (EV-C) assigned to different tag groups in phylogenetic trees constructed from 250 base sequence fragments sequentially generated across the viral genome alignment. Segregation by serotype occurs only in the VP4-VP1 (capsid encoding region) and is disrupted by recombination events elsewhere [14]. (B) Phylogenetic compatibility matrix of the same dataset show frequency of inter-group phylogeny violations between trees generated from different genome regions.