Table 1.
Baselines characteristics.
| FeSO4a n = 74 |
Placebo n = 71 |
Differencea Absolute values |
|
|---|---|---|---|
| Age, mean years (SD) | 32.9 (8.4) | 30.7 (8.8) | 2.1 |
| Number of previous donations per year, n (%) | |||
| None | 26 (35.1%) | 25 (35.2%) | -0.1% |
| One | 29 (39.2%) | 31 (43.7%) | -4.5% |
| Two | 19 (25.7%) | 15 (21.1%) | 4.6% |
| Weight, mean kg (SD) | 64.2 (10.7) | 67.6 (13.3) | -3.4 |
| Pictorial Bleeding Assessment chart | |||
| Score > 185, n (%) | 6 (8.2%) | 9 (12.7%) | -4.5%a |
| Before donation; mean (SD) | |||
| Visual analogue scale for fatigue | 3.4 (2.4) | 3.9 (2.6) | -0.6 |
| Fatigue severity scale | 2.5 (1.1) | 2.7 (1.2) | -0.2 |
| Hemoglobin, g/Lb | 138 (6.3) | 135 (7.5) | 3 |
| Ferritin, ng/mLb | 36.3 (22.4) | 34.1 (15.0) | 2.2 |
| One week after donation; mean (SD) | |||
| Visual analogue scale for fatigue | 3.9 (2.3) | 4.0 (2.4) | -0.02 |
| Fatigue severity scale | 2.9 (1.3) | 3.0 (1.4) | -0.1 |
| Vitality score (SF-12V2)c | 53.1 (12.9) | 55.9 (11.3) | -2.8 |
| Chester step test, mLO2/kg/min | 37.0 (7.2) | 36.9 (5.9) | 0.1 |
| Hemoglobin, g/L | 126 (5.2) | 126 (5.3) | -0.02 |
| Ferritin, ng/mL | 15.3 (7.7) | 14.8 (7.3) | 0.4 |
| C-reactive protein, mg/L | 2.1 (2.9) | 2.9 (3.5) | 0.8 |
| Depression (PHQ-9), n (%) | 4 (5.4%) | 4 (5.7%) | -0.3% |
| Mental health (SF-12NL)d | 38.6 (4.4) | 39.3 (5.3) | -0.7 |
| Physical condition (SF-12NL)d | 53.7 (4.2) | 53.6 (4.2) | 0.09 |
aClinically significant difference. P-values of differences were not calculated, since randomization and allocation ensured that any difference could only be due to chance. bHemoglobin and ferritin values before donation were not available for two donors from the control group. cOne donor from the intervention group and two from the control group did not answer the 10th question on the SF-12V2. dSF-12 was incomplete for three donors in each group. SD: standard deviation.