. Author manuscript; available in PMC: 2012 Dec 22.

Published in final edited form as: J Med Chem. 2011 Nov 23;54(24):8471–8489. doi: 10.1021/jm201018g

Table 10.

Average IC₅₀ (from n independent experiments in μM) of selected arylsulfonamide HIF-1 pathway inhibitors as established in the HRE-luciferase assay.

Name	# of repeats	IC₅₀	Std. Error	95% CI
1	42	0. 648	0.044	(0.562, 0.734)
16a	6	0.306	0.06	(0.187, 0.425)
5g	6	0.813	0.141	(0.533, 1.093)
16d	6	0.478	0.105	(0.270, 0.686)
16f	6	0.378	0.062	(0.255, 0.501)
26i	30	0.280	0.022	(0.237, 0.323)

CI - Confidence Interval.