TABLE I.

Evaluation of CpG Sites in Differentially Methylated Genes From the Literature

Probe ID	Gene	Reference	PTSD diagnosis		Child abuse		TLS
			T-statistic	P-value	T-statistic	P-value	T-statistic	P-value
cg13384396	ADCY5	Uddin et al. [2010]	2.71	0.0080	NS	NS	NS	NS
cg16967583	AGXT	Uddin et al. [2010]	2.11	0.038	NS	NS	NS	NS
cg19224278	ALDH1A3	Uddin et al. [2010]	2.03	0.045	NS	NS	NS	NS
cg24921089	AMPD3	Uddin et al. [2010]	2.73	0.0075	NS	NS	NS	NS
cg11098259	AQP9	Uddin et al. [2010]	NS	NS	NS	NS	NS	NS
cg27351358	BDNF	Roth et al. [2009]	3.33	0.0012	NS	NS	−2.00	0.049
cg16257091	BDNF	Roth et al. [2009]	2.01	0.047	NS	NS	NS	NS
cg17118262	CCL1	Uddin et al. [2010]	NS	NS	−2.38	0.019	NS	NS
cg16719404	CD2	Uddin et al. [2010]	−3.18	0.002	NS	NS	NS	NS
cg00298951	CMKLR1	Uddin et al. [2010]	NS	NS	NS	NS	NS	NS
cg02029926	CXCL1	Uddin et al. [2010]	2.13	0.036	NS	NS	2.80	0.0062
cg04451770	ENTPD1	Uddin et al. [2010]	3.00	0.0034	NS	NS	NS	NS
cg13471990	ENTPD1	Uddin et al. [2010]	NS	NS	−3.13	0.0022	NS	NS
cg06306751	F8	Uddin et al. [2010]	NS	NS	−2.03	0.045	NS	NS
cg09001777	FUT3	Uddin et al. [2010]	3.39	0.0010	NS	NS	NS	NS
cg07970007	GBP1	Uddin et al. [2010]	−1.98	0.050	NS	NS	NS	NS
cg13406950	GBP1	Uddin et al. [2010]	NS	NS	−2.59	0.011	NS	NS
cg15125472	HSPB6	Uddin et al. [2010]	3.51	6.93 × 10−4	NS	NS	NS	NS
cg24673765	HSPB6	Uddin et al. [2010]	2.03	0.045	NS	NS	NS	NS
cg07463059	IFI16	Uddin et al. [2010]	NS	NS	NS	NS	2.23	0.028
cg08090640	IFI35	Uddin et al. [2010]	NS	NS	NS	NS	3.15	0.0021
cg23915111	KIF14	Uddin et al. [2010]	NS	NS	NS	NS	3.23	0.0017
cg14913610	KLRG1	Uddin et al. [2010]	2.10	0.038	NS	NS	NS	NS
cg21092324	MMRN1	Uddin et al. [2010]	NS	NS	NS	NS	NS	NS
cg25482967	MRPS10	Uddin et al. [2010]	NS	NS	2.66	0.0092	NS	NS
cg20318748	NANP	Uddin et al. [2010]	NS	NS	2.30	0.023	NS	NS
cg07042144	NLRP12	Uddin et al. [2010]	NS	NS	NS	NS	NS	NS
cg20842040	PRPS2	Uddin et al. [2010]	3.16	0.0022	NS	NS	NS	NS
cg07874284	PRPS2	Uddin et al. [2010]	2.24	0.028	NS	NS	NS	NS
cg19769182	PRRT2	Uddin et al. [2010]	2.44	0.017	NS	NS	NS	NS
cg02740947	RAD51L3	Uddin et al. [2010]	NS	NS	NS	NS	−2.19	0.031
cg07837085	SLAMF7	Uddin et al. [2010]	2.16	0.034	NS	NS	NS	NS
cg21554249	SUOX	Uddin et al. [2010]	2.01	0.047	NS	NS	NS	NS
cg03430998	TLR1	Uddin et al. [2010]	NS	NS	NS	NS	2.11	0.037

NS indicates genes that were not significant with respect to the outcome at P < 0.05. Additionally, CpG sites in ATP1A1, BBS7, CD1D, CSNK1D, CYP2J2, DGAT2L6, GALR2, HOXD10, IL8, ISLR2, LST1, LTA4H, MRI1, MTPN, NALP2, NR3C1, NUMB, PTGIS, PTPN22, PYDC1, RIF1, SCN5A, SLC6A4, SOSTDC1, SRXN1, STAP1, STC1, TREM1, TFPI, TLR3, TNC, and TRAP1 were not associated at P < 0.05 with any outcome examined.