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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: J Gene Med. 2011 Oct;13(10):557–565. doi: 10.1002/jgm.1600

Figure 1.

Figure 1

Activity of heart gene delivery research since its inception. Pubmed is searched using the MeSH term ‘heart and gene therapy’. The number of publications is plotted against the year. The time of introduction of each vector is marked. An explosive increase in the number of heart gene delivery papers is noticed after AAV vector is introduced. The first clinical trial of gene therapy for advanced heart failure was initiated in 2007. AAV vector was used in the trial. Each vector is not drawn to scale.