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Distribution of TP53 codon 72 genotypes across the two groups of subjects defined on the basis of the in vivo mtDNA heteroplasmy levels. Obs: observed; Exp: expected under random combination between heteroplasmy and TP53 genotypes (p-value= p=0.0147).
| Levels of heteroplasmy | Genotype | Total | |||||
|---|---|---|---|---|---|---|---|
| RR | RP | PP | |||||
| Obs (%) | Exp | Obs (%) | Exp | Obs (%) | Exp | ||
| ≤ 5% | 127 (57.2) | 116 | 75 (33.8) | 87.2 | 20 (9.0) | 18.8 | 222 |
| > 5% | 95 (46.8) | 106 | 92 (45.3) | 79.8 | 16 (7.9) | 17.2 | 203 |
| Total | 222 | 167 | 36 | 425 | |||
