Table 1.
Summary of the clinical and histological data of 18 patients with primary and recurrent gliomas
| Case | Age (y) | Sex | Site of tumor | Interval of biopsies (m) | Survival (m) | Histology P/R | Adjuvant therapy |
|---|---|---|---|---|---|---|---|
| 1 | 20 | M | RTL | 15 | ALIVE | PA2 | R |
| RTL | RA3 | - | |||||
| 2 | 48 | M | LTL | 24 | ALIVE | PA2 | R |
| LTL | RA3 | - | |||||
| 3 | 55 | M | RFL | 13 | 14 | PA3 | - |
| RFL | RA3 | - | |||||
| 4 | 50 | F | LTL | 74 | ALIVE | PA2 | R |
| LTL | RA3 | T | |||||
| 5 | 30 | M | RFL | 662 | ALIVE | PA2 | R |
| RFL | RA3 | - | |||||
| 6 | 41 | F | RTL | 42 | 64 | PA2 | R |
| RTL | RA3 | - | |||||
| 7 | 50 | M | LOL | 9 | 18 | PA3 | R |
| LOL | RGB | T | |||||
| 8 | 15 | F | LFL | 31 | 49 | PA3 | R |
| LFL | RGB | CVP | |||||
| 9 | 27 | F | RFL | 33 | 98 | PA3 | R |
| RFL | RGB | T | |||||
| 10 | 56 | F | RPL | 12 | 32 | PA3 | R |
| RPL | RGB | - | |||||
| 11 | 69 | F | RFL | 11 | 16 | PGB | R |
| RFL | RGB | - | |||||
| 12 | 44 | M | LPL | 3 | 6 | PGB | R |
| LPL | RGB | - | |||||
| 13 | 47 | M | LFL | 9 | 12 | PGB | - |
| LFL | RGB | T | |||||
| 14 | 55 | M | LTL | 13 | 19 | PGB | R |
| LTL | RGB | T | |||||
| 15 | 62 | M | RFL | 6 | 18 | PGB | R |
| RFL | RGB | T | |||||
| 16 | 54 | M | RTL | 12 | 14 | PGB | R |
| RTL | RGB | T | |||||
| 17 | 41 | M | RTL | 10 | 24 | PGCGB | R |
| RTL | RGCGB | T | |||||
| 18 | 17 | F | RTL | 15 | 29 | PGCGB | R |
| RTL | RGCGB | CVP | |||||
Abbreviations: Histology: P for primary and R for recurrence; A2, diffuse astrocytoma; A3, anaplastic astrocytoma; GB, glioblastoma; GCGB, giant cell glioblastoma; LFL, left frontal lobe; RFL, right frontal lobe; LTL, left temporal lobe; RTL, right temporal lobe; RPL, right parietal lobe; ROL, right occipital lobe; R, radiotherapy; CVP, Carbo/VP-16 chemotherapy; T, Temodal; female; M, male; y, year; m, month; Interval is the time in months between the two biopsies