Table 1.

Characteristic differences in expression of 14-3-3 protein isoforms in the different stages of follicular development as observed by immunohistochemical staining of adult mouse ovarian sections

Feature	Isoform	Stage of Ovarian Follicle
		Secondary	Early Antral	Graafian
Expression in zonae pellucidae around oocytes	14-3-3 β 14-3-3 γ 14-3-3 ε 14-3-3 ζ 14-3-3 η 14-3-3 τ 14-3-3 σ	++ + ++ + - ++ ++	++ + ++ + - ++ ++	++ + ++ - - ++ ++
Prominent lack of expression in peripheral mural granulosa cells	14-3-3 β 14-3-3 γ 14-3-3 ε 14-3-3 ζ 14-3-3 η 14-3-3 τ 14-3-3 σ	Yes Yes Yes No Yes Yes Yes	Yes No No No No No No	Yes Yes Yes No No Yes Yes
Marked accumulation in granulosa cells surrounding the antrum	14-3-3 β 14-3-3 γ 14-3-3 ε 14-3-3 ζ 14-3-3 η 14-3-3 τ 14-3-3 σ		Yes Yes No No No No Yes	Yes Yes Yes Yes Yes Yes Yes

'++' = Considerable expression; '+' = Some expression;

'-' = Non-detectable expression; 'Yes' = Presence of the feature; 'No' = Feature not detectable