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Serum auto-antibody activity for dsDNA or α-actinin assessed by ELISA. Serum samples from γ3 +/+ (green), +/- (yellow), and -/- (red) mice were tested for binding of total IgG (left panel) to double stranded (ds) DNA (circles) or to α-actinin (squares), and for binding of IgG3 (right panel) to dsDNA (diamonds) or to α-actinin (triangles).
