Figure 9.

Quantification of LGE. (A) Identical LV short-axis contrast-enhanced cardiovascular MR images show LGE depicted with gray-scale thresholding techniques at 2, 4, and 6 SDs above mean signal intensity of normal remote myocardium, with visual assessment, and with 2 SDs above mean of external region of interest (ROI). LV endocardium and epicardium are outlined in red and green, respectively. Solid black areas in LV myocardium represent areas of delayed enhancement at corresponding semiautomated threshold; (B) Graph illustrates volumes of delayed enhancement (horizontal axis values) assessed by using various gray-scale thresholding techniques (2, 4, and 6 SDs above mean), visual assessment, and an external region of interest. Reproduced with permission, from Harrigan C et al.[113]