Table 2.

Prognostic value of reduced admission eGFR for 30-day and long-term mortality according to gender

Variable	Mortality
	Male HR (95% CI)	p Value		Female HR (95% CI)	p Value	P for interaction
Thirty-day mortality
Univariable
eGFR <60 ml/min	12.6 (8.10 to 19.7)	<0.001	6.27 (3.53 to 11.1)		<0.001	<0.001
Multivariable
eGFR <60 ml/min	13.59 (5.67 to 32.61)	<0.001	6.42 (1.89 to 21.9)		0.003
Age	1.00 (0.97 to 1.04)	0.90	1.04 (1.01 to 1.07)		<0.01
Multivariable*
eGFR <60 ml/min	11.58 (5.39 to 24.91)	<0.001	3.41 (1.38 to 8.44)		0.008	0.005
Multivariable*
eGFR 45–60 ml/min	7.29 (2.84 to 18.72)	<0.001	2.39 (0.86 to 6.61)		0.095
eGFR <45 ml/min	16.11 (7.17 to 36.21)	<0.001	7.82 (2.64 to 23.17)		<0.001
Long-term mortality
Univariable
eGFR <60 ml/min	9.39 (6.73 to 13.10)	<0.001	4.74 (3.15 to 7.13)		<0.001	<0.001
Multivariable
eGFR <60 ml/min	5.09 (3.38 to 7.69)	<0.001	2.54 (1.56 to 4.13)		<0.001
Age	1.04 (1.02 to 1.06)	<0.001	1.05 (1.02 to 1.07)		<0.001
Multivariable*
eGFR <60 ml/min	6.31 (3.74 to 10.63)	<0.001	2.22 (1.25 to 3.94)		0.006	0.03
Multivariable*
eGFR 45–60 ml/min	3.58 (1.79 to 7.14)	<0.001	1.65 (0.86 to 3.15)		0.131
eGFR <45 ml/min	5.73 (2.68 to 12.27)	<0.001	4.15 (2.04 to 8.43)		<0.001

For all Cox models. The reference category for the eGFR variable is eGFR ≥60 ml/min.

^*Adjusted for age, body mass index, history of diabetes or hypertension systolic blood pressure and pulse, anterior myocardial infarction and time to treatment.

eGFR, estimated glomerular filtration rate.