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. 2012 Mar 5;2:301. doi: 10.1038/srep00301

Figure 1. The dynamics of haloperidol-induced catalepsy in GRK6 deficient mice.

Figure 1

The histograms illustrate the time the animals spent to remove both front paws from the bar (as index of cataleptic behavior). All the animals were tested at 1, 2, 3 and 4 hours (T1, T2, T3 and T4) after the drug injection. 1A. Effect of haloperidol 0.5 mg/kg, i.p. 4 groups: WT Saline (n = 12) and Haloperidol (n = 7); GRK6-KO Saline (n = 13) and Haloperidol (n = 7). 1B. Effect of haloperidol 1 mg/kg, i.p. 4 groups: WT Saline (n = 12) and Haloperidol (n = 19); GRK6-KO Saline (n = 13) and Haloperidol (n = 21). 1C. Effect of haloperidol 2 mg/kg, i.p. 4 groups: WT saline (n = 12) and Haloperidol (n = 17); GRK6-KO saline (n = 13) and Haloperidol (n = 19). *p<0.05 vs Saline in the same group of genotype; # p<0.05 vs WT in the same group of dose (Bonferroni post-hoc).