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. Author manuscript; available in PMC: 2012 Mar 5.
Published in final edited form as: Clin Trials. 2011 Aug;8(4):370–379. doi: 10.1177/1740774511410732

Table 3.

True Toxicity Rates at each dose level di

True Toxicity Rates: P(Y=2) jP(Y=1) jP(Y=0)
Scenario 1 Scenario 2 Scenario 3 Scenario 4
d 1 .10 |.38 |.52 .05 |.33 |.62 .01 |.22 |.77 .01 |.22 |.77
d 2 .15 |.39 |.46 .10 |.38 |.52 .04 |.32 |.64 .05 |.33 |.62
d 3 .20 |.40 |.40 .15 |.39 |.46 .08 |.37 |.55 .07 |.36 |.57
d 4 .30 |.38 |.32 .20 |.40 |.40 .12 |.39 |.49 .10 |.38 |.52
d 5 .45 |.32 |.23 .30 |.38 |.32 .20 |.40 |.40 .12 |.39 |.49
d 6 .50 |.30 |.20 .40 |.35 |.35 .30 |.38 |.32 .20 |.40 |.40

Y = 0; 1; 2 corresponds to no toxicity, moderate, and dose limiting toxicity respectively.