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. Author manuscript; available in PMC: 2012 Mar 5.
Published in final edited form as: Oral Dis. 2011 Jun 27;17(6):601–609. doi: 10.1111/j.1601-0825.2011.01819.x

Figure 4. Examples of ANA speckled nuclear staining patterns detected in δKO sera.

Figure 4

HEp-2 slides were incubated with WT and δKO sera diluted 1:100 followed by anti-mouse IgG conjugated to FITC (green). Examples of nuclear coarse speckled (CS), fine speckled (FS), dense fine speckled (DFS) and negative (NEG) staining patterns as detected in δKO sera are shown. A rating of the intensity of staining (1 through 3) was also assigned based on signal intensity by 3 different evaluators (Table 1).