Tab. 4.
Comp. | Na | log GI50 | log TGI | log LC50 | ||||||
---|---|---|---|---|---|---|---|---|---|---|
| ||||||||||
N1b | Range | MG_MID | N2b | Range | MG_MID | N3b | Range | MG_MID | ||
3.14 | 57 | −55 | −6.07 to −5.01 | −5.48 | 17 | −5.53 to −4.02 | −4.21 | 5 | −5.46 to −4.04 | −4.05 |
3.16 | 59 | 59 | −6.29 to −5.31 | −5.52 | 58 | −5.44 to −4.64 | −4.89 | 50 | −5.11 to −4.07 | −4.32 |
3.18 | 59 | 59 | −6.29 to −5.31 | −5.57 | 59 | −5.54 to −4.55 | −5.04 | 56 | −5.24 to −4.01 | −4.51 |
N – number of human tumor cell lines tested at the 2nd stage assay;
N1, N2, N3 – number of sensitive cell lines, against which the compound possessed considerable growth inhibition according to mentioned parameter (log GI50, log TGI and log LC50 ≤ 4.00).