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. 2011 Dec 23;80(1):37–65. doi: 10.3797/scipharm.1111-15

Tab. 4.

Summary of anticancer screening data at dose-dependent assay

Comp. Na log GI50 log TGI log LC50

N1b Range MG_MID N2b Range MG_MID N3b Range MG_MID
3.14 57 −55 −6.07 to −5.01 −5.48 17 −5.53 to −4.02 −4.21 5 −5.46 to −4.04 −4.05
3.16 59 59 −6.29 to −5.31 −5.52 58 −5.44 to −4.64 −4.89 50 −5.11 to −4.07 −4.32
3.18 59 59 −6.29 to −5.31 −5.57 59 −5.54 to −4.55 −5.04 56 −5.24 to −4.01 −4.51
a

N – number of human tumor cell lines tested at the 2nd stage assay;

b

N1, N2, N3 – number of sensitive cell lines, against which the compound possessed considerable growth inhibition according to mentioned parameter (log GI50, log TGI and log LC50 ≤ 4.00).