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. 2011 Dec 23;80(1):37–65. doi: 10.3797/scipharm.1111-15

Tab. 5.

The influence of compounds 3.14, 3.16 and 3.18 on the growth of individual tumor cell lines (log GI50 ≤ −5.65)

Cpd. Cancer Cell line log GI50 log TGI Log LC50
3.14 Leukemia RPMI-8226 −5.70 > −4.00 > −4.00
SR −5.83 > −4.00 > −4.00
NSC lung cancer A549/ATCC −5.66 > −4.00 > −4.00
Colon cancer HCT-116 −5.66 −4.97 > −4.00
HT29 −5.74 > −4.00 > −4.00
CNS cancer SF-539 −5.80 −5.50 −5.21
SNB-75 −6.07 −4.90 −4.36
Melanoma LOX IMVI −5.88 −5.53 −5.18
Renal cancer A498 −5.88 −4.51 > −4.00
ACHN −5.88 −5.46 −5.46
CAKI-1 −5.94 > −4.00 > −4.00
UO-31 −5.79 −4.61 > −4.00

3.16 Colon cancer COLO 205 −5.76 −5.37 −4.93
HT29 −5.66 −4.91 > −4.00
CNS cancer SF-539 −5.67 −5.22 −4.62
SNB-75 −5.72 −4.87 −4.43
Melanoma LOX IMVI −5.76 −5.44 −5.11
SK-MEL-5 −5.66 −5.23 −4.67
UACC-257 −5.68 −5.29 −4.77
Renal cancer A498 −6.29 −5.21 −4.51
ACHN −5.68 −4.93 −4.33
CAKI-1 −5.66 −4.98 −4.07
UO-31 −5.79 −5.07 −4.43

3.18 Leukemia RPMI-8226 −5.71 −5.31 −4.51
NSC lung cancer A549/ATCC −5.77 −5.48 −5.20
HOP-92 −6.20 −5.14 −4.47
NCI-H460 −5.80 −5.49 −5.19
NCI-H522 −5.80 −5.49 −5.18
Colon cancer COLO 205 −5.88 −5.54 −5.20
HCT-116 −5.93 −5.42 −4.79
HT29 −5.96 −5.50 −5.03
SW-620 −5.65 −4.96 −4.43
CNS cancer SF-539 −5.79 −5.45 −5.10
SNB-75 −5.81 −5.33 −4.70
U251 −5.78 −5.46 −5.15
Melanoma LOX IMVI −5.89 −5.28 −4.61
MALME-3M −5.68 −5.29 −4.65
SK-MEL-5 −5.74 −5.34 −4.86
UACC-257 −5.79 −5.51 −5.24
UACC-62 −5.79 −5.38 −4.79
Ovarian cancer OVCAR-3 −5.78 −5.46 −5.15
OVCAR-4 −5.75 −5.33 −4.82
OVCAR-8 −5.84 −5.46 −5.08
Renal cancer 786-0 −5.73 −5.33 −4.84
ACHN −5.81 −5.20 −4.45
RXF 393 −5.75 −5.34 −4.74
Prostate cancer PC-3 −5.70 −5.01 −4.47
Breast cancer MCF7 −5.81 −5.39 −4.90
MDA-MB-231/ATCC −5.76 −5.17 −4.48
MDA-MB-468 −5.75 −5.37 −4.98