Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2012 Mar 5.

Published in final edited form as: Toxicon. 2007 Oct 13;51(2):297–303. doi: 10.1016/j.toxicon.2007.10.004

Table 3.

Comparison of NACSA and Coralymn

Characteristics	NACSA	Coralmyn
Produced	United States of America	Mexico
Origin	Equine	Equine
Antibody Type	IgG	(Fab’)2
Molecular Weight	110 kDa	50 kDa
Reconstitution (min)	45^a	Immediate^b
Distribution (h)	>3^c	3 ^c
Elimination (h)	>100 ^c	60 ^c
Tissue Affinity	High ^c	Moderate-High ^c
Elimination Route	Immune Tissue ^c	Immune Tissue ^c
Binds Complement	Yes ^c	No ^c
ED₅₀ ^d	1 vial (10 mL) neutralizes 250 LD₅₀	1 vial (5 mL) neutralizes 450 LD₅₀

^a

Kanavage et al., 2006

^b

Current study

^c

Chippaux and Goyffon, 1998

^d

Manufacture’s antivenom insert information