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. Author manuscript; available in PMC: 2012 Mar 5.
Published in final edited form as: Toxicon. 2011 Feb 18;57(5):794–802. doi: 10.1016/j.toxicon.2011.02.014

Table 1.

Adhesion of T24 and SK-MEL-28 cells to fibronectin in presence of mojastin disintegrins.

Disintegrin Inhibition of cell
adhesion T24 cellsa
Inhibition of cell
adhesion
SK-Mel-28 cellsa
GST-r-Mojastin 200 nM 16 nM
r-Mojastin 1 NA 95 nM
Native mojastin NA 113 nM

NA = No activity.

Commercial echistatin used as positive control at 1.8 µM completely inhibited SK-MEL-28 and T24 cells adhesion to fibronectin.

a

The results are expressed as IC50