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. 2012 Feb 29;7(2):e32738. doi: 10.1371/journal.pone.0032738

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Mao et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Western blot analysis showed that Na_V1.5 protein was significantly decreased (*p<0.05) in HL-1 cells treated with 25 µM H₂O₂ for 48 h hours (n = 3) compared with the control group (n = 3) (A, C). RT-PCR analysis showed that Na_V1.5 mRNA significantly reduced (p*<0.05) in HL-1 cells treated with 25 µM H₂O₂ for 48 hours (n = 3) compared with the control group (n = 4) (B, D).