DNA-binding domains contacting DNA by utilizing β-sheets.
a, ERF domain of Arabidopsis AtERF1 (Protein Data Bank code 1GCC). b, THAP zinc finger domain of human THAP1 (code 2KO0). c, larger subdomain of the GCM domain of Drosophila GCM (code 1ODH). Red spheres in b and c indicate zinc ions. The DNA-binding mode in c, as well as that of the WRKY domain, is termed the β-wedge (see “Results and Discussion”). The figures were produced by MOLMOL (41).