Table 4.
Starting doses of TKIs
TKI | Dose, mg/m2 | Frequency | Dosage strength, mg |
---|---|---|---|
Imatinib | 340 | Once daily | 100, 400 |
Dasatinib | 60-80 | Once daily | 20, 50, 70, 80, 100, 140 |
Nilotinib* | 170-230 | Twice daily | 150, 200 |
Pediatric dosing has not been established but is based on 300 mg or 400 mg twice daily if less than or greater than 40 kg, respectively.