Table 5.

Instructions to prepare liquid suspension of TKIs

TKI	Instructions
Imatinib	Tablets may be dispersed in water or apple juice using 50 mL for 100-mg tablet or 200 mL for 400-mg tablet. The contents must be stirred until dissolved and used immediately. For children < 3 y old, it is recommended that at least 120 mL of water or food be taken to avoid esophageal irritation.
Dasatinib	Tablets can be allowed to dissolve over 20 minutes at room temperature in 30 mL of lemonade, preservative-free apple juice, or preservative-free orange juice. After ingestion, rinse the residue off glass with 15 mL of the juice and administer.
Nilotinib	Capsules may be dispersed in 5 mL of applesauce and ingested immediately on an empty stomach, and abstain from eating for at least 1 hour.