Table 4.
Cumulative psychiatric diagnoses for participants scanned as young adults (19 years or older). (All diagnoses were based on outcome of a CIDIa interview if performed after age 19 or K-SADS interview performed between the ages of 8–18).
| High risk (N=38) | Low risk (N=26) | |
|---|---|---|
| Alcohol or drug abuse | 13 (34.2) | 3 (11.5) |
| Alcohol or drug dependence | 12 (31.6) | 7 (26.9) |
| Either abuse or dependenceb | 13 (34.2) | 3 (11.5) |
| Anxiety disorders | 13 (34.2) | 8 (30.8) |
| Depression | 9 (23.7) | 3 (11.5) |
| Attention deficit hyperactivity disorder (ADHD)c | 4 (11.8) | 0 (0) |
| Oppositional/conduct disorderc | 9 (26.5) | 0 (0) |
a
Composite International Diagnostic Interview.
b
A significantly greater proportion of high than low risk offspring met criteria for substance use disorder defined as either abuse or dependence on alcohol or drugs (χ2=4.23, d.f.=1, p=0.04).
c
This diagnosis was available only from the K-SADS.