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. 2012 Mar 5;7(3):e32431. doi: 10.1371/journal.pone.0032431

Figure 3. Restriction of RA9 CD8 T cell epitope to Mane-A*10.

Figure 3

(A) CD8 T cell response to influenza RA9 peptide in influenza vaccinated animal 26359 (B) Expansion of RA9 specific CD8 T cells. RA9-specific CD8 T cell response in fresh blood is shown in comparison to a 2 week in vitro expansion as described in methods. (C) Mane-A*10 restriction of RA9 response. Transfected (Mane-A*10 or Mane-B*02) and untransfected C1R cells were pulsed with either DMSO or RA9 peptide. These C1R cells were incubated separately with in vitro cultured RA9-specific CD8 T cells and IFN-γ and TNF-α expression measured.