Table 3. Variance components of serum haptoglobin concentrations (656 families/2680 individuals, rs2000999 & rs4788597 as allelic frequency).
Model 1 | Model 2 | Model 3 | |
Adjustment for | None | Age & BMI | Age, BMI & rs2000999 allelic frequency |
Polygenic variance: σ2 G | 0.0478±0.0120***, 24.9% | 0.0460±0.0109***, 26.0% | 0.0226±0.0101*, 14.2% |
Household variance: σ2 H | 0.0250±0.0065***, 13.0% | 0.0206±0.0059***, 11.6% | 0.0233±0.0053***, 14.7% |
Residual variance: σ2 E | 0.1194±0.0078***, 62.1% | 0.1103±0.0072***, 62.4% | 0.1130±0.0069***, 71.1% |
Loge L2 (Logarithm of likelihood function) | −968.90 | −1074.58 | −1200.04 |
Alternate model | - | Model 1 | Model 2 |
χ2 (df) | - | 211.36 (8) | 250.92 (4) |
P | - | *** | *** |
P≤0.05,
P≤0.01,
*** P≤0.001.
BMI: body mass index.