Table 4. Discovery and replication of rs2000999 association data for Hp levels.

					Haptoglobin (g/L)
Population	Stage	N	MAF	GG	GA	AA	β	Standard error	raw P	P adjusted with rs10492825
SFS - unrelated children	Discovery	631	0.21	0.736±0.406	0.532±0.321	0.361±0.180	−0.123	0.017	6.32×10−13	1.95×10−07
SFS - families	Replication	2,957	0.20	1.056±0.467	0.819±0.445	0.549±0.330	−0.138	0.007	1.17×10−75
Obese children	Replication	1,015	0.22	1.261±0.492	1.064±0.455	1.002±0.534	−0.088	0.013	1.20×10−11
GENDAI	Replication	419	0.25	0.811±0.450	0.813±0.558	0.731±0.319	−0.021	0.021	0.306
Replication sample	Replication	4,391	0.22						3.49×10−41
Overall meta-analysis	Replication	5,022							8.09×10−59

N: sample size; MAF: Minor Allele Frequency; β:beta coefficient for the effect allele A.