Skip to main content

View full-text article in PMC

. 2012 Mar 5;7(3):e32620. doi: 10.1371/journal.pone.0032620

Table 2. Ex vivo chemosusceptibility values for endoperoxides.

Lines	ARTEMISININ				ARTESUNATE				ARTEMETHER		ARTEMISONE
	pressure		release		pressure		release		pressure		pressure
	IC₅₀	RI	IC₅₀	RI	IC₅₀	RI	IC₅₀	RI	IC₅₀	RI	IC₅₀ (nM)	RI
Y-control	0.17±0.04^Ψ	1	-	-	0.04±0.002	1	-	-	0.03±0.006	1	0.02±0.002	1
Y-ART1	1.8±0.84^*Ψ	11	nd	-	0.43±0.04^*	11	nd	-	0.6±0.075*	18	0.37±0.025*	19
Y-ART2	45±11.3^*	264	nd	-	3.47±2.06^*	87	nd	-	1.6±0.53*	53	0.57±0.12^#	29
Y-ART3	0.8±0.11^*Ψ	5	0.06 ± 0.009	0.4	0.38±0.01^*	10	0.02±0.003	0.3	0.4±0.06*	14	0.28±0.04*	14
Y-CQ1	1.36±0.03^*Ψ	8	0.05 ± 0	0.3	0.51±0.23^*	13	0.02±0.003	0.3	0.6±0.008*	18	0.42±0.025*	21
Y-CQ2	0.9±0.2^*Ψ	5	nd	-	0.40±0.10^*Ψ	10	nd	-	0.5±0.033*	15	0.31±0.037*	16