Table 3. Ex vivo chemosusceptibility values for not-lysosomotropes.
Lines | SULFADOXINE-PYRIMETHAMINE | ATOVAQUONE | ||||
pressure | release | pressure | ||||
IC50† | RI | IC50† | RI | IC50 (nM) | RI | |
Y-control | 6.5±1.16 | 1 | nd | - | 32.2±5.7 | 1 |
Y-ART1 | 4.50# | 0.7 | nd | - | 23.9±14.3* | 0.7 |
Y-ART2 | 5.1±0.73 | 0.8 | nd | - | 70.1±19 | 2.2 |
Y-ART3 | 5.9±1.23 | 0.9 | 5.5±0.74 | 0.84 | 23.6±4.9* | 0.7 |
Y-CQ1 | 5.0±0.9 | 0.8 | 4.5±0.13 | 0.7 | 18.6±3.2* | 0.6 |
Y-CQ2 | 5.0??? | 0.8 | nd | - | 20.5±9.5* | 0.6 |