Skip to main content
. 2012 Mar 5;7(3):e32749. doi: 10.1371/journal.pone.0032749

Figure 4. Optimization of experimental design for model discrimination.

Figure 4

A - Optimal initial concentrations of methylglyoxal and glutathione (solutions approximating the Pareto front) for the discrimination of the two models presented in figure 2. B – Corresponding values of the extended Kullback-Leibler distances (optimization objectives); Concentration of glyoxalase I is 2.0×10−3 mM and concentration of glyoxalase II is 4.0×10−4 mM. The red dot indicates the initial concentrations used in the discriminatory experiment.