Table 1.

Expressing mRme-1 G429R results in decreased MPR uptake

TRVb-1 cells stably transfected with chimeric MPR were transiently transfected with FLAG-mRme-1 G429R. Cells were incubated with Cy3-anti-bCI-MPR for 5 min followed by chase in the absence of Cy3-anti-bCI-MPR for 2.5 min or for 30 min. Data from a representative experiment are shown.

Cells	Experiment	% of CI-MPR uptake	No. of cells
Control	5-min uptake	100	23
mRme-1 G429R	5-min uptake	57	64
Control	2.5-min chase	100	11
mRme-1 G429R	2.5-min chase	56	40
Control	30-min chase	100	21
mRme-1 G429R	30-min chase	54	108