Skip to main content
. 2012 Mar 5;7(3):e32159. doi: 10.1371/journal.pone.0032159

Table 1. Main characteristics of all studies included in the meta-analysis.

Study Ethnicity Genotyping method Source of control PHWE Frequency of G allele Cases/Controls No. of cases No. of controls
GG GA AA GG GA AA
Tanabe 2008a16 Mixed PCR-RFLP HB 0.19 0.001 59/148 23 27 9 32 65 51
Tanabe 2008b16 Caucasian PCR-RFLP HB 0.99 0.04 44/77 15 17 12 12 37 28
Abu 201117 Mixed allele-specific PCR HB 0.08 0.08 66/750 24 25 17 180 350 220
Chen 201118 Chinese-Han PCR-RFLP HB and PB 0.56 0.11 120/240 62 51 7 106 110 24
Li 200919 Chinese-Han PCR-RFLP HB and PB 0.94 0.12 186/338 96 82 8 161 145 32
Qi 200920 Chinese-Han PCR-RFLP HB and PB 0.75 0.55 215/380 102 98 15 182 160 38
Wang 2009a21 Chinese* PCR-RFLP HB 0.37 0.06 397/480 200 163 34 209 222 49
Wang 2009b21 Chinese-Han PCR-RFLP HB 0.53 0.06 217/200 125 76 16 94 89 17

Abbreviations: PCR-RFLP, polymerase chain reaction-restriction fragment length polymorphism; PB, population-based; HB, hospital-based; PHWE, Hardy-Weinberg equilibrium of controls.

*

Included multiple ethnicities in China.