Table 4. SV, SVR, APP and PIP during the experimental period.
Parameter | Group | 0 h | 3 h | 6 h | 9 h | 12 h |
SV(ml) | SAP+IAP30 | 45.5±4.4 | 21.7±3.0* # ∧ | 15.8±4.5* # ∧ | 13.0±1.4* # + ∧ | 11.8±1.6* # + ∧ |
SAP+IAP20 | 48.1±4.3 | 21.7±5.2* # ∧ | 15.9±2.9* # ∧ | 13.1±1.0* # + ∧ | 12.8±1.5* # + ∧ | |
SAP | 45.0±7.1 | 29.3±3.1 | 21.0±3.3 | 18.2±3.3 | 20.0±4.8 | |
IAP30 | 49.0±5.5 | 30.7±3.2 | 30.2±1.9 | 31.0±3.3 | 40.5±5.3 | |
Sham | 49.2±6.7 | 39.5±4.2 | 40.2±5 | 40.5±5.3 | 39.5±4.4 | |
SVR(dyne/s/cm5) | SAP+IAP30 | 1359±104 | 2077±270* ∧ | 2443±432* ∧ | 2339±319* ∧ | 2486±201* ∧ |
SAP+IAP20 | 1430±191 | 2063±394* ∧ | 2286±549* ∧ | 2226±459* ∧ | 2113±462* ∧ | |
SAP | 1497±228 | 1908±495 | 2618±727 | 2684±648 | 2397±576 | |
IAP30 | 1345±89 | 1725±191 | 1744±155 | 1980±249 | 1974±206 | |
Sham | 1340±149 | 1386±134 | 1364±141 | 1406±143 | 1396±143 | |
APP(mmHg) | SAP+IAP30 | 83.7±6.9 | 72.7±7.3∧ | 62.3±8.0* + ∧ | 46.5±11.5* # + ∧ | 45.3±3.5* # + ∧ |
SAP+IAP20 | 88.2±8.9 | 75.0±8.0∧ | 67.5±7.5* + ∧ | 57.0±8.4* + ∧ | 50.5±7.5* # + ∧ | |
SAP | 90.5±9.9 | 85.2±14.1 | 93.5±16.1 | 89.8±9.7 | 89.5±9.2 | |
IAP30 | 94.5±8.5 | 64.8±6.2 | 65.8±4.8 | 72±9.2 | 73.5±6.5 | |
Sham | 91.3±13.4 | 91.3±6.1 | 93.0±9.1 | 93.0±7.3 | 91.5±7.9 | |
PIP(cmH2O) | SAP+IAP30 | 17.8±2.3 | 50.0±3.0▵ * + ∧ | 50.0±2.8▵ * + ∧ | 49.2±2.4▵ * + ∧ | 50.0±1.0▵ * + ∧ |
SAP+IAP20 | 17.3±2.8 | 40.5±1.6* # + ∧ | 39.3±1.8* + ∧ | 38.4±2.5* # + ∧ | 37.6±1.0* # + ∧ | |
SAP | 17.0±2.5 | 16.8±0.8 | 16.7±1.6 | 18.3±1.6 | 22.8±2.4 | |
IAP30 | 18.3±2.7 | 47.3±3.4 | 45.3±4.3 | 47.2±3.7 | 45.5±3.4 | |
Sham | 18.2±2.6 | 19.2±1.0 | 19.0±2.8 | 19.5±2.2 | 19.8±2.7 |
SV: stroke volume; SVR: systemic vascular resistance; APP: abdominal perfusion pressure; PIP: peak inspiratory pressure; SAP: severe acute pancreatitis; IAP: intra abdominal pressure;
Significant difference vs. SAP+IAP20 group;
Significant difference vs. sham group;
significant difference vs. IAP30 group;
significant difference vs. SAP group;
significant difference vs. baseline values.