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. 2012 Mar 5;7(3):e33125. doi: 10.1371/journal.pone.0033125

Table 4. SV, SVR, APP and PIP during the experimental period.

Parameter Group 0 h 3 h 6 h 9 h 12 h
SV(ml) SAP+IAP30 45.5±4.4 21.7±3.0* # 15.8±4.5* # 13.0±1.4* # + 11.8±1.6* # +
SAP+IAP20 48.1±4.3 21.7±5.2* # 15.9±2.9* # 13.1±1.0* # + 12.8±1.5* # +
SAP 45.0±7.1 29.3±3.1 21.0±3.3 18.2±3.3 20.0±4.8
IAP30 49.0±5.5 30.7±3.2 30.2±1.9 31.0±3.3 40.5±5.3
Sham 49.2±6.7 39.5±4.2 40.2±5 40.5±5.3 39.5±4.4
SVR(dyne/s/cm5) SAP+IAP30 1359±104 2077±270* 2443±432* 2339±319* 2486±201*
SAP+IAP20 1430±191 2063±394* 2286±549* 2226±459* 2113±462*
SAP 1497±228 1908±495 2618±727 2684±648 2397±576
IAP30 1345±89 1725±191 1744±155 1980±249 1974±206
Sham 1340±149 1386±134 1364±141 1406±143 1396±143
APP(mmHg) SAP+IAP30 83.7±6.9 72.7±7.3 62.3±8.0* + 46.5±11.5* # + 45.3±3.5* # +
SAP+IAP20 88.2±8.9 75.0±8.0 67.5±7.5* + 57.0±8.4* + 50.5±7.5* # +
SAP 90.5±9.9 85.2±14.1 93.5±16.1 89.8±9.7 89.5±9.2
IAP30 94.5±8.5 64.8±6.2 65.8±4.8 72±9.2 73.5±6.5
Sham 91.3±13.4 91.3±6.1 93.0±9.1 93.0±7.3 91.5±7.9
PIP(cmH2O) SAP+IAP30 17.8±2.3 50.0±3.0 * + 50.0±2.8 * + 49.2±2.4 * + 50.0±1.0 * +
SAP+IAP20 17.3±2.8 40.5±1.6* # + 39.3±1.8* + 38.4±2.5* # + 37.6±1.0* # +
SAP 17.0±2.5 16.8±0.8 16.7±1.6 18.3±1.6 22.8±2.4
IAP30 18.3±2.7 47.3±3.4 45.3±4.3 47.2±3.7 45.5±3.4
Sham 18.2±2.6 19.2±1.0 19.0±2.8 19.5±2.2 19.8±2.7

SV: stroke volume; SVR: systemic vascular resistance; APP: abdominal perfusion pressure; PIP: peak inspiratory pressure; SAP: severe acute pancreatitis; IAP: intra abdominal pressure;

Significant difference vs. SAP+IAP20 group;

*

Significant difference vs. sham group;

#

significant difference vs. IAP30 group;

+

significant difference vs. SAP group;

significant difference vs. baseline values.