Table 5. Oxygenation-derived parameters during the experimental period.
| Parameter | Group | 0 h | 3 h | 6 h | 9 h | 12 h |
| Lactate(mmol/L) | SAP+IAP30 | 0.95±0.16 | 1.97±0.28∧ | 2.87±0.79* ∧ | 3.60±0.80* # + ∧ | 3.80±0.94* + ∧ |
| SAP+IAP20 | 0.80±0.24 | 1.77±0.45∧ | 2.63±0.66* ∧ | 3.48±0.57* + ∧ | 3.92±0.81* + ∧ | |
| SAP | 0.90±0.14 | 1.38±0.31 | 1.95±0.42 | 2.05±0.24 | 2.08±0.31 | |
| IAP30 | 1.03±0.33 | 1.68±0.33 | 2.05±0.28 | 2.30±0.38 | 2.58±0.48 | |
| Sham | 0.90±0.17 | 1.28±0.33 | 1.27±0.22 | 1.18±0.33 | 1.05±0.21 | |
| SVO2(%) | SAP+IAP30 | 71.0±2.9 | 51.1±2.2* # + ∧ | 42.0±5.7* # + ∧ | 40.5±5.6* # + ∧ | 40.2±5.9* # + ∧ |
| SAP+IAP20 | 76.2±3.7 | 58.9±3.8* ∧ | 48.5±7.2* # ∧ | 42.3±2.9* # + ∧ | 40.5±3.8* # + ∧ | |
| SAP | 71.4±3.5 | 64.6±8.2 | 60.8±8.1 | 52.9±5.1 | 53.6±5.5 | |
| IAP30 | 73.1±5.0 | 65.8±7.9 | 64.9±7.4 | 60.5±6.6 | 61.0±9.9 | |
| Sham | 71.6±4.3 | 69.8±3.5 | 71.1±5.1 | 71.2±4.4 | 72.0±2.5 | |
| PO2(mmHg) | SAP+IAP30 | 86.0±6.1 | 77.9±5.8* ∧ | 72.9±4.4* ∧ | 74.6±2.6* # ∧ | 75.4±2.5* ∧ |
| SAP+IAP20 | 91.7±9.0 | 82.5±4.8∧ | 74.6±5.4* ∧ | 70.4±2.8* # + ∧ | 74.1±5.3* ∧ | |
| SAP | 91.5±11.9 | 89.8±14.2 | 87.9±11.0 | 86.1±9.7 | 83.7±10.6 | |
| IAP30 | 91.0±4.1 | 89.8±7.0 | 84.0±7.7 | 83.3±5.4 | 81.2±2.9 | |
| Sham | 88.3±4.1 | 88.4±4.3 | 89.2±6.5 | 88.5±5.7 | 88.5±5.1 | |
| Base excess | SAP+IAP30 | 4.0±1.8 | 0.4±2.3* # ∧ | −0.7±1.4* # + ∧ | −1.8±2.0* # + ∧ | −1.6±1.6* # + ∧ |
| SAP+IAP20 | 4.0±1.0 | 1.1±0.9# ∧ | 0.0±0.9* # + ∧ | −1.1±1.2* # + ∧ | −1.6±1.6* # + ∧ | |
| SAP | 4.5±1.2 | 3.6±1.3 | 4.2±1.3 | 3.3±1.1 | 2.9±1.2 | |
| IAP30 | 3.4±1.1 | 4.0±0.9 | 3.8±1.3 | 2.6±1.2 | 2.4±1.4 | |
| Sham | 4.3±1.1 | 4.1±1.4 | 4.6±1.4 | 4.6±1.3 | 4.5±1.2 |
SAP: severe acute pancreatitis; IAP: intra abdominal pressure; SVO2: mixed venous oxygen saturation; PO2: partial pressure of oxygen;
*
Significant difference vs. sham group;
#
significant difference vs. IAP30 group;
+
significant difference vs.SAP group;
∧
significant difference vs. baseline values.