Table 6. Biochemical parameters during the experiment period.
Parameter | Group | 0 h | 3 h | 6 h | 9 h | 12 h |
Amylase(U/L) | SAP+IAP30 | 595±153 | 2877±841* # ∧ | 4665±901* # ∧ | 5773±1107* # ∧ | 6766±1945* # ∧ |
SAP+IAP20 | 680±160 | 2923±680* # ∧ | 4690±847* # ∧ | 5472±1141* # ∧ | 6455±2099* # ∧ | |
SAP | 709±153 | 2629±859 | 3882±1525 | 4428±1334 | 5195±1019 | |
IAP30 | 748±139 | 1400±373 | 1788±198 | 1953±194 | 2087±107 | |
Sham | 680±144 | 1194±265 | 1392±344 | 1493±255 | 1488±194 | |
AST(U/L) | SAP+IAP30 | 77±10 | 164±26* # ∧ | 213±28* # + ∧ | 262±44* # + ∧ | 279±34* # + ∧ |
SAP+IAP20 | 57±12 | 153±27* # ∧ | 190±30* ∧ | 233±48* ∧ | 279±46* # + ∧ | |
SAP | 86±15 | 119±22 | 145±25 | 160±24 | 168±29 | |
IAP30 | 80±19 | 99±14 | 141±18 | 163±18 | 191±12 | |
Sham | 80±17 | 86±20 | 91±19 | 94±12 | 97±8 | |
SUN(mmol/L) | SAP+IAP30 | 3.15±0.99 | 5.82±1.60∧ | 8.53±1.34* # + ∧ | 10.68±2.02* # + ∧ | 10.92±1.25* # ∧ |
SAP+IAP20 | 2.57±0.48 | 4.48±1.09∧ | 7.70±1.48* # ∧ | 9.72±2.07* # + ∧ | 10.77±2.50* # ∧ | |
SAP | 3.35±0.54 | 4.12±0.99 | 5.18±1.47 | 5.88±1.68 | 7.12±1.54 | |
IAP30 | 3.26±0.62 | 3.52±0.53 | 3.78±0.43 | 4.28±0.44 | 4.70±0.75 | |
Sham | 3.33±0.73 | 3.80±0.64 | 4.08±0.52 | 3.88±0.67 | 4.10±0.85 | |
Creatinine(µmol/L) | SAP+IAP30 | 74±24 | 151±22* # ∧ | 225±37* # ∧ | 287±25* # + ∧ | 314±29* # + ∧ |
SAP+IAP20 | 72±12 | 148±25* # ∧ | 197±30* # ∧ | 241±33* # ∧ | 313±36* # + ∧ | |
SAP | 76±18 | 131±33 | 177±35 | 205±28 | 226±243 | |
IAP30 | 67±11 | 92±11+ | 106±10 | 149±23 | 181±30 | |
Sham | 77±18 | 90±18 | 96±20 | 99±15 | 105±15 |
SAP: severe acute pancreatitis; IAP: intra abdominal pressure; AST: Aspartate transaminase; SUN: serum urea nitrogen;
Significant difference vs. sham group;
significant difference vs. IAP30 group;
significant difference vs.SAP group;
significant difference vs. baseline values.