Skip to main content
. 2012 Mar 5;7(3):e33100. doi: 10.1371/journal.pone.0033100

Figure 5. Mutant JAK2 exon 12 allele burden in bone marrow and peripheral blood cell lineages.

Figure 5

Histogram plot displaying the JAK2 exon 12 mutation burden in bone marrow, peripheral blood, CD16+ granulocytes, CD14+ monocytes, CD3+ T-lymphocytes, and CD19+ B-lymphocytes in patients PV1-PV6. PV2 had very low level of JAK2 exon 12 mutant allele burden except for the bone marrow sample. PV1-PV3 and PV5 appeared to be heterozygous, whereas PV4 and PV6 were homozygous. Note that DNA from bone marrow samples could not be obtained from patients PV5 and PV6. BM, bone marrow and PB, peripheral blood.