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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Infect Genet Evol. 2011 Nov 20;12(2):282–290. doi: 10.1016/j.meegid.2011.11.006

Figure 5. Annual selection coefficients on dhfr (A), dhps (B) and combined dhfr-dhps (C) haplotypes.

Figure 5

Plotted points are point estimates.

Plotted points are the slope of a regression line fitted to a plot of the ln(R/S) plotted against parasite generations (assumed 6/year), where R is the frequency of the mutant haplotype indicated, and S is the frequency of other haplotypes. Annual selection coefficients were calculated as the slope of the line fitted to the ln(R/S) for the year of interest and the preceding and subsequent years. Values greater than zero represent a haplotype survival advantage in subsequent parasite generations; those less than zero indicate a survival disadvantage.