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. Author manuscript; available in PMC: 2013 Mar 15.
Published in final edited form as: J Immunol. 2012 Feb 15;188(6):2778–2793. doi: 10.4049/jimmunol.1101380

Figure 5. Comparison of DEP and Carbon Black Effects on M.tb- and PPD-induced Cytokine Production.

Figure 5

PBMC from healthy subjects (n= 3) were stimulated with M.tb at MOI 10 and PPD (10 µg/mL) in presence of varying doses of DEP or carbon black (CB). DEP or CB was added at final concentrations of 0 (DEP0, CB0, negative control), 1, 10, and 50 µg/mL. Numbers of IFN-γ, IL-10 and TNF-α-producing PBMC were enumerated by ELISPOT assay and frequencies of cytokine-producing cells (y-axes) are plotted as a function of DEP concentration in µg/mL (x-axes shown below the TNF-α panel only). Mean frequencies ± standard error of the mean is shown.