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. Author manuscript; available in PMC: 2012 Mar 6.
Published in final edited form as: Lancet. 2012 Jan 27;379(9818):823–832. doi: 10.1016/S0140-6736(11)61941-7

Table 2.

Cox proportional hazards models for 5 year overall mortality in the Kaiser Permanente validation cohort

Univariate analysis
 Multivariate analysis
Hazard ratio
(95% CI)		 Wald test
p value		 Hazard ratio
(95% CI)		 Likelihood ratio
test p value
Risk category*
 High risk 2·16 (1·39–3·36) 0·0007 2·04 (1·28–3·26) 0·0016
 Intermediate risk 1·60 (0·98–2·60) 0·0610 1·66 (1·00–2·74) 0·0436
Age >65 years 1·55 (1·14–2·10) 0·0054 1·66 (1·21–2·29) 0·0016
Sex (female) 0·55 (0·41–0·74) 0·0001 0·67 (0·49–0·92) 0·0123
Never smoker 0·59 (0·32–1·09) 0·0917 0·83 (0·44–1·55) 0·5438
Histology†
 Large-cell carcinoma 0·96 (0·42–2·17) 0·9139 0·64 (0·26–1·59) 0·3038
 Mixed 0·98 (0·43–2·22) 0·9615 0·85 (0·37–1·95) 0·6932
 NSCLC (not otherwise specified) 1·13 (0·89–1·93) 0·1659 1·18 (0·79–1·75) 0·4320
Tumour size >4 cm 1·42 (0·97–2·07) 0·0697 1·10 (0·73–1·66) 0·6435

NSCLC=non-small-cell lung cancer.

*

Compared with low-risk group.

†

Compared with adenocarcinoma.