Table 1.
Col1a1+/+ | Col1a1R/R | ||||||
---|---|---|---|---|---|---|---|
Normoxia (n=7) | Hypoxia (n=5) | Recovery (n=7) | Normoxia (n=7) | Hypoxia (n=5) | Recovery (n=5) | ||
PA pressure [mm Hg] | Systolic | 19±3 | 31± 5* | 26± 7 | 20±5 | 33±5* | 22±7† |
Diastolic | 7±4 | 18± 3*** | 15± 6* | 8±3 | 20±5** | 11±6† | |
Mean | 11±3 | 23± 3*** | 19± 7* | 13±3 | 25±5*** | 15±6† | |
Aortic pressure [mm Hg] | Systolic | 73±24 | 82±37 | 84±19 | 72±25 | 69±28 | 56±5 |
Diastolic | 24±11 | 41±13 | 49±17 | 20±14 | 40±14 | 12±5 | |
Mean | 39± 5 | 50±12 | 59±19 | 35±6 | 45±19 | 25±3 | |
HR [bpm] | 540±45 | 562±47 | 617±28* | 540±48 | 569±63 | 530± 53 | |
MPA inner diam. [mm] | 1.3±0.2 | 1.3±0.2 | 1.4±0.1 | 1.3±0.2 | 1.4±0.2 | 1.4±0.1 | |
CO [ml/min] | 11±3 | 9±2 | 11±2 | 10±3 | 12±5 | 9±3 | |
Hct [−] | 60± 6 | 81± 5*** | 51± 4††† | 56±4 | 85±4*** | 57±7††† |
p<0.05 vs. Normoxia,
p<0.005 vs. Normoxia,
p<0.0005 vs. Normoxia,
p<0.05 vs. Hypoxia,
p<0.0005 vs. Hypoxia.