Figure 3. Asymmetric gene expression is affected when apical-basal or planar cell polarity is disrupted.

(A): Xnr-1 localization in embryos injected with DNPar6. In all images, green arrows indicate correct left-sided expression, red arrows indicate ectopic expression, and white arrows indicate absent expression. A.i) Normal left-sided expression of Xnr-1, as observed in the majority of untreated embryos. A.ii) Right-sided expression. A.iii) Bilateral expression. A.iv) Absent Xnr-1 expression. Similar localization patterns were observed for other reagents that disrupt ABP and PCP signaling (not shown). B) Graph of inappropriate Xnr-1 expression observed in untreated and injected embryos. All groups are significantly different from controls (*p<0.001). Numbers on graph indicate sample sizes.