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. Author manuscript; available in PMC: 2013 May 10.
Published in final edited form as: Virology. 2012 Feb 16;426(2):120–133. doi: 10.1016/j.virol.2012.01.025

Figure 3. BNSP-Gag-GM-CSF expresses GM-CSF that has physiological effects on DCs in vivo.

Figure 3

6–8 week old BALB/c mice were immunized with 1 × 105 FFU of either BNSP-Gag, BNSP-Gag-IFN(−) or BNSP-Gag-GM-CSF. 3 days later the spleens, draining lymph nodes and blood were harvested and stained with antibodies against surface markers of DCs – CD11c and CD11b (a) and activation marker - CD86 and CD11c (b). Statistical analysis was performed using one-WAY ANOVA and Students t-tests. Numerical statistical values were obtained by t-test whereas P values indicated by * were obtained by ONE-WAY ANOVA test. * P <0.05, ** P<0.01.