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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Neurobiol Aging. 2011 Dec 1;33(10):2247–2261. doi: 10.1016/j.neurobiolaging.2011.10.027

Figure 6. AD brains had elevated protein phospho-tyrosine and active phospho-Src levels compared to age-matched controls.

Figure 6

AD and age-matched control (c) temporal lobe lysates (n=6) were resolved by 10% SDS-PAGE and Western blotted using (A) anti phospho-Tyr (4G10), anti-Aβ (6E10), anti-α-tubulin (loading control) antibodies, (C) anti-Lyn, anti-phospho-Lyn (Tyr396), anti-Src, and anti-phospho-Src antibodies. Optical density of (B) Total phospho-Tyr or Aβ multimers and (D) pLyn and pSrc from 6 AD and age-matched control brain blots were normalized to their respective α-tubulin blots or total protein levels (Lyn/Src) then averaged and graphed (+/−SD). (*p< 0.001)