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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Dev Biol. 2012 Jan 18;364(1):42–55. doi: 10.1016/j.ydbio.2012.01.008

Figure 2. Overexpression of Arg induced gastrulation defects in early Xenopus embryos.

Figure 2

Ectopic expression of Arg led to failure of blastopore closure, reduced head structure and shortened body axis at neurula (A, dorsal view) or tadpole (B, side view) stages. The effects were dose-dependent, so that more severe defects (open back) were observed in a larger portion of the embryos when the doses of Arg RNA were increased (C). The expression level of Arg was shown in panel D.