Figure 3. IA treatment attenuates neurological deficits in mice following ischemia.
All mice were subjected to 1 h of cerebral ischemia followed by 24 h of reperfusion. Animals were injected with vehicle (control) or IA at 1, 10 or 50 mg/kg i.p. at the end of the ischemic period. Neurological deficits were measured at the end of reperfusion (22 h) as outlined in the Experimental procedures. *p < 0.04 for IA (1 mg/kg) compared to control; **p < 0.0001 for IA (10 or 50 mg/kg) compared to control.
