Figure 4. IA inhibits the expression of inflammatory mediators following ischemia.
Mice were subjected to 1 h of ischemia followed by 6 h of reperfusion. Animals treated with IA at the indicated doses were examined for the levels of: A. TNF-α; B. IL-1β and C. TGF-β. Quantitative analysis of cytokines in the ischemic brain was determined via ELISA. *p < 0.05; **p < 0.0001 compared to controls.
