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. Author manuscript; available in PMC: 2013 Mar 14.
Published in final edited form as: Brain Res. 2012 Jan 9;1443:89–97. doi: 10.1016/j.brainres.2012.01.001

Figure 6. Effects of IA on infarct volumes and neurological deficits with various times for treatment.

Figure 6

Mice were subjected to 1 h of cerebral ischemia followed by 48 hours of reperfusion. Animals were injected with vehicle (control) or IA at 50 mg/kg i.p. at various times after the end of the ischemic period. A. Infarct volumes in mice subjected to time course of IA treatment. Animals were sacrificed after 48 hours and processed to determine the infarct volume. B. Neurological deficits in mice subjected to time course of IA treatment. Neurological deficits were measured at the end of reperfusion as outlined in the Experimental procedures. *p < 0.0001 for all groups compared to control except for t = 12 or 24 h, p ≥ 0.05.