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. Author manuscript; available in PMC: 2013 Mar 15.
Published in final edited form as: J Immunol. 2012 Feb 13;188(6):2894–2904. doi: 10.4049/jimmunol.1101391

Figure 5.

Figure 5

Neonatal RV infection induces prolonged changes in airway inflammation. Cells from the minced lungs of 35 day-old mice infected with sham or RV at 7 days of age were analyzed by flow cytometry. Compared to sham-exposed mice, RV-infected mice showed significant increases in (A) Gr1-positive neutrophils and (B) Gr1-, SigF-double-positive and eosinophils, (C) CD4-positive T cells, (E) CD19-positive B cells and (F) CD11b-positive cells. There was no change in the number of CD8-positive cells (D). RV infection increased the CD206 expression of CD11b-positive cells (G; sham, grey line; RV, black line). Lung digests from RV-infected mice showed increases in the percentage of CD4-positive T cells expressing IFN-γ (H) and CD335-positive NK cells expressing IL-13 (I). N = 5–6 animals per group, *different from sham-exposed neonatal mice, p<0.05, rank sum test.