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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Ann Rheum Dis. 2011 Nov 14;71(4):575–581. doi: 10.1136/annrheumdis-2011-200557

Figure 5. Effect of Rapamycin on inflammation in experimental OA.

Figure 5

A, Synovium from mice after experimental OA and vehicle (N= 16) or rapamycin (rapa, N= 11) treatment was analyzed by staining with Safranin O. Magnification: 40×. B, The histological score for inflammation was significantly decreased after rapa treatment. Values are the mean ± SD. * = P < 0.05 versus OA-vehicle. C, Synovium sections from vehicle or rapa treated mice (N=5 each) were analyzed by immunohistochemistry for IL-1β. Magnification: 40×.