Table 5.
One-way ANOVA comparing HRQOL (generic scale and cancer scale) between children on- and off-treatment (≤ 12 months or > 12 months): self- and proxy-report (bold)
| Scales | Child On-treatment (a) | Child off-treatment (b) | Child off-treatment (c) | Difference | F | P | |||
|---|---|---|---|---|---|---|---|---|---|
| ≤ 12 months | > 12 months | Value | |||||||
| n | mean (SD) | n | Mean (SD) | n | Mean (SD) | ||||
| Generic Scale | |||||||||
| Total score | 110 | 65.42 (16.98) | 26 | 67.14 (18.05) | 66 | 73.69 (16.19) | a < c** | 5.04 | 0.007 |
| 157 | 62.33 (16.70) | 35 | 65.92 (19.43) | 74 | 71.22 (17.92) | a < c*** | 6.58 | 0.002 | |
| Physical functioning | 110 | 62.57 (21.08) | 26 | 67.12 (18.25) | 66 | 76.26 (19.24) | a < c***, b < c* | 9.53 | 0.000 |
| 157 | 61.55 (18.67) | 35 | 66.18 (20.63) | 74 | 75.51 (21.15) | a < c***, b < c* | 12.7 | 0.000 | |
| Psychosocial functioning | 110 | 67.94 (17.53) | 26 | 67.23 (19.77) | 66 | 72.20 (18.92) | 1.30 | 0.275 | |
| 157 | 63.07 (19.40) | 35 | 66.04 (17.36) | 74 | 68.87 (18.56) | 2.42 | 0.091 | ||
| Emotional functioning | 110 | 64.71 (19.54) | 26 | 67.36 (22.81) | 66 | 73.64 (20.16) | a < c** | 4.05 | 0.019 |
| 157 | 59.82 (24.58) | 35 | 68.40 (21.82) | 74 | 70.71 (18.44) | a < b*, a < c*** | 6.44 | 0.002 | |
| Social functioning | 110 | 77.97 (17.48) | 26 | 75.03 (18.24) | 66 | 79.30 (15.68) | 0.59 | 0.556 | |
| 157 | 72.02 (20.68) | 35 | 72.26 (18.52) | 74 | 75.16 (18.79) | 0.65 | 0.524 | ||
| School functioning | 86 | 58.47 (19.89) | 20 | 60.35 (18.55) | 59 | 65.18 (23.09) | 1.81 | 0.167 | |
| 107 | 57.96 (19.30) | 26 | 60.80 (22.25) | 62 | 62.94 (24.35) | 1.08 | 0.342 | ||
| Cancer scale | |||||||||
| Pain and hurt | 110 | 70.23 (20.54) | 26 | 75.35 (20.19) | 66 | 78.66 (22.47) | a < c* | 3.38 | 0.036 |
| 157 | 74.68 (19.03) | 35 | 77.81 (21.45) | 74 | 82.12 (20.60) | a < c** | 3.57 | 0.029 | |
| Nausea | 110 | 63.92 (22.36) | 26 | 78.72 (19.11) | 66 | 83.20 (18.59) | a < b**, a < c*** | 19.22 | 0.000 |
| 157 | 66.81 (18.29) | 35 | 72.34 (23.05) | 74 | 81.72 (16.14) | a < c***, b < c* | 16.5 | 0.000 | |
| Procedural anxiety | 110 | 63.17 (28.31) | 26 | 70.29(25.25) | 66 | 73.33 (24.90) | a < c* | 3.12 | 0.046 |
| 157 | 62.42 (22.63) | 35 | 64.71 (25.39) | 74 | 76.26 (24.87) | a < c***, b < c* | 8.74 | 0.000 | |
| Treatment anxiety | 110 | 68.77 (23.48) | 26 | 72.11 (26.23) | 66 | 73.84 (20.64) | 1.05 | 0.352 | |
| 157 | 62.85 (20.69) | 35 | 68.05 (24.38) | 74 | 72.97 (23.38) | a < c** | 5.46 | 0.005 | |
| Worry | 110 | 66.59 (23.24) | 26 | 70.33 (28.10) | 66 | 71.32 (25.61) | 0.83 | 0.438 | |
| 155 | 59.13 (22.00) | 35 | 60.78 (24.43) | 72 | 67.20 (24.74) | a < c* | 3.06 | 0.049 | |
| Cognitive problems | 108 | 70.09 (25.65) | 26 | 73.83 (30.02) | 66 | 71.75 (29.45) | 0.22 | 0.804 | |
| 154 | 72.11 (23.96) | 34 | 74.44 (29.12) | 72 | 74.25 (26.92) | 0.23 | 0.791 | ||
| Perceived physical appearance | 110 | 74.85 (19.48) | 26 | 76.98 (22.17) | 66 | 79.65 (18.34) | 1.24 | 0.291 | |
| 154 | 77.21 (16.90) | 34 | 74.93 (20.55) | 73 | 75.77 (17.49) | 0.32 | 0.723 | ||
| Communication | 110 | 72.66 (19.11) | 26 | 73.27 (18.40) | 65 | 70.98 (22.75) | 0.18 | 0.832 | |
| 155 | 71.18 (22.83) | 35 | 75.29 (24.52) | 72 | 72.04 (22.38) | 0.46 | 0.633 | ||
*P < 0.05, **P < 0.01, ***P < 0.001 based on Tukey Honestly Significantly Different post hoc analysis.